15
Nov
A-SIDE
Contact:
- Beijing-Leicester-London-New Jersey
- mintviv[a]gmail.com
Education:
- PhD in Pharmacology (Thesis), University of Leicester, U.K. 2005-2009
- MSc in Molecular Genetics, University of Leicester, U.K. 2004-2005
- MB in Clinical Medicine, Capital Medical University, P.R.China. 1999-2004
Work Experience:
- Postdoctoral Fellow, New Jersey Medical School-UMDNJ, U.S.A. Mar 2011-present
NIH funded researches focus on the roles of myocyte receptors (e.g. TRPC, mitochondria/SR receptors) in ventricular arrhythmia and to discover novel physiological/pharmacological pathways for therapeutic targets in heart failure. - Postdoctoral Research Fellow, William Harvey Research Institute, Queen Mary, University of London, U.K. Jan 2009-Jan 2011
Wellcome trust funded researches focus on the roles of TRPV1 in vascular regulations. - Research Associate, University of Leicester, U.K. Oct 2008-Dec 2008
A short term contract of investigating the regulation of carboxyl terminus to P2X1 receptor function, funded by British Heart Foundation. - Teaching Assistant, Teaching experiment preparations, experimental skills demonstrations and reports marking for BSc/BMS students in Biomedical Sciences at physiological practicals.
- Research Assistant, University of Leicester, U.K. Jan 2007-Dec 2007
Duties included Xenopus oocytes defoliculation and micro-injections, glassware and tips autoclaving, general lab tiding, and lab COSSH database management, this work was funded by Wellcome trust. - Diabetes Investigator, Accenture, P.R.China. May 2003
Queen Mary, University of London, U.K. Nov 2009-Mar 2010
Measurement of metabolic rate and factors affecting MR (2010) ; The Control of breathing (2010).
University of Leicester, U.K. Feb 2006-May 2008
Respiratory gases & metabolism (2008); Venous occlusion plethysmography (2006-2007).
Special Skills:
- Cell culture and primary tissue culture ; Langendorff isolated heart perfusion/ Myocytes isolation; Xenopus oocyte isolation/defoliculation/micro-injection; Small animal handling and surgery;
Molecular biology ; Biochemical techniques; Immunohistochemical staining;
Confocal and fluorescent calcium imaging; Cell contractility measurement; Two-electrodes voltage clamping, Whole cell & Single channel patch clamping; Optical heart mapping; in vivo EKG/VEP recording;
Full clinical trainings for 12 months.
- English: skilled in daily and academic communication; French:basic daily communication; Chinese: native mandarin user.
- Proficient user of MS office, scientific software; experience in website and graphic design.
Other Experience & Achievements:
- Winner of American Heart Association Scientific Council (Council of Basic Cardiovascular Sciences) Travel Grant (2011).
- Presentations on Neuroscience and Trauma Research Seminar Series (2010), and BICMS Core Facilities Day (2010).
- Presented works in departmental seminars and lab meetings 2005-2011.
- Shortlisted for William Harvey Young Investigator Award 2009.
- University Scholarships for excellent academic performance and social work in 1999,2002 & 2004.
- Member of American Heart Association (2011-2013).
- Member of Cardiac Electrophysiology Society 2011.
- Associate of The New York Academy of Sciences (2011-2012).
- Member of Red Cross of China and holder of First Aid Certificate 2000.
- Drug Design and Discovery Training at AstraZeneca 2007 .
- Tour to Centre of the Cell 2009 .
- Demonstrator for Dynamic DNA Day 2008 .
- Chief Editor of University TV Station (1999-2001) and Departmental Magazine (2000-2004).
Conferences:
- Scientific Sessions of American Heart Association 2011 (Orlando, Florida, U.S.A);
- Cardiac Electrophysiology Society Annual Meeting 2011 (Orlando, Florida, U.S.A);
- WorldPharma 2010 (Copenhagen, Denmark);
- William Harvey Day 2009 & 2010 (London, U.K.);
- Barts and The London’s Annual Pain Symposium 2009 (London, U.K.);
- PURINES 2008 (Copenhagen, Denmark);
- European Biophysics Congress: Ion Channels 2007 (Leeds, U.K.);
- International Symposium on Adenosine and Adenine Nucleotides 2006 (Ferrara, Italy).
Publications:
- Revisiting the Ionic Mechanisms of Early Afterdepolarizations in Cardiomyocytes: Predominant by Ca Waves or Ca Currents?(2012). American Journal of Physiology – Heart and Circulatory Physiology.[link]
- Identification of novel somatic mutation in sarcolipin gene in human fetal atrial standstill (2011). Circulation.[link]
- A unique “Cellular Fibrillation” status in mouse ventricular myocytes (2011).Circulation.[link]
- Arrhythmogenic effect of store-operated calcium entry in mouse ventricular myocytes (2011).Circulation.[link]
- Sex specific role for TRPV1 in pressure induced constriction of resistance arteries (2010).pA2 online.[link]
- Contribution of the intracellular C terminal domain to regulation of human P2X1 receptors for ATP by phorbol ester and Gq coupled mGlu1α receptors (2010). European Journal of Pharmacology. [link]
- 20-HETE exhibits two phosphorylation-dependent actions on TRPV1 (2010). William Harvey Day 2010.
- 20-HETE activation of TRPV1 in small diameter primary sensory neurons （2010).Basic & Clinical Pharmacology & Toxicology .[link]
- Tethered-toxin debut gets cold reception (2010). Journal of Physiology. [link]
- 20-HETE activation of the vanilloid receptor TRPV1 (2009). William Harvey Day 2009.
- Regions of the amino terminus of the P2X1 receptor required for modification by phorbol ester and mGluR1a receptor (2009). Journal of Neurochemistry. [link]
- The roles of the P2X1 receptor amino terminus in regulation by phorbol ester and GPCRs (2008). Purinergic Signalling.[link]
- Molecular physiology and pharmacology of P2X1 receptor (2006). Purinergic Signalling.[link]
- Molecular properties of P2X receptors (2006). Pflugers Archiv European Journal of Physiology. [link]
